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submitted on 03.08.2020 and posted on 04.08.2020by Eddy Wei
Ping Tan, James L. Hedrick, Pedro Luis Arrechea, Tim Erdmann, Vivien Kiyek, Simon Lottier, Yi Yan Yang, Nathaniel Park
Accessing cyclic carbonate monomers on large scales is critical for development of
any new carbonate-based material platform. This is particularly important in the context of using
automated experimental systems for materials synthesis, which can often require large inputs of
starting materials. However, the synthesis of carbonate monomers can be a challenging and tedious
endeavor, requiring multiple synthetic steps and purifications. To address this, we report a
drastically improved and scalable process for the synthesis of carbonate monomers via a two-step route that avoids the use of hazardous phosgene or chloroformate reagents. The cyclic carbonate
monomers can be obtained in high yields and with minimal need for chromatographic purification.
This process enables rapid access to a broad array of functional groups on the carbonate monomer
and monomers generated from procedure can readily be polymerized via ring-opening