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The Air-Water Interface Stabilises Alpha-Helical Conformations of the Insulin B-Chain
preprintrevised on 10.07.2019, 08:07 and posted on 10.07.2019, 13:21 by David Cheung
Using enhanced molecular dynamics simulations the structure of the insulin B-chain was investigated at the air-water interface and in bulk solution. Significant differences in the conformational behaviour between these environments were found, with the air-water interface stabilising the formation of alpha-helical structures.