ChemRxiv
These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
insulin.pdf (4.81 MB)
0/0

The Air-Water Interface Stabilises Alpha-Helical Conformations of the Insulin B-Chain

preprint
revised on 10.07.2019 and posted on 10.07.2019 by David Cheung
Using enhanced molecular dynamics simulations the structure of the insulin B-chain was investigated at the air-water interface and in bulk solution. Significant differences in the conformational behaviour between these environments were found, with the air-water interface stabilising the formation of alpha-helical structures.

History

Email Address of Submitting Author

david.cheung@nuigalway.ie

Institution

National University of Ireland Galway

Country

Ireland

ORCID For Submitting Author

0000-0002-3994-2295

Declaration of Conflict of Interest

no conflict of interest

Exports

Logo branding

Exports