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A new class of tetrasubsituted imidazole based compounds were synthesized using
multicomponent one pot synthesis scheme through cyclocondensation reaction of benzil,
aromatic primary amines, aldehydes and ammonium acetate in glacial acetic acid. The
synthesized compounds have been analyzed and characterized by melting point, color,
conductivity method, CHN analysis, FT-IR and UV-Visible. The reaction proceeding was
examined by TLC after regular intervals of period. To test biological activity, the synthesized
compounds have been examined against various bacterial strains. From the analysis of the
antibacterial activity of these synthesized compounds demonstrated that all three imidazole
compounds have considerable to significant activity against the strains, and compound K2 was
found potent comparatively.