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Superelectrophilic Aluminum(III)-Ion Pairs Promote a Distinct Reaction Path for Carbonyl-Olefin Metathesis of Medium-Sized Rings
preprintsubmitted on 27.09.2019, 00:07 and posted on 30.09.2019, 18:11 by Rebecca Watson, Ashlee J. Davis, Jessica L. Gomez-Lopez, Daniel Nasrallah, Corinna Schindler
We describe the development of a new catalyst system for carbonyl-olefin ring-closing metathesis reactions that relies on Lewis acidic superelectrophiles and significantly expands the current scope of this transformation to medium-sized rings.
Importantly, these superelectrophiles are shown to promote carbonyl-olefin metathesis via a distinct and unprecedented mechanism.