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Sulfoxide Synthesis from Sulfinate Esters under Pummerer-like Conditions

preprint
submitted on 26.03.2020, 07:49 and posted on 26.03.2020, 12:09 by Akihiro Kobayashi, Tsubasa Matsuzawa, Takamitsu Hosoya, Suguru Yoshida
A facile synthetic method of allyl sulfoxides by S-allylation of sulfinate esters through sulfonium intermediates has been developed without [3,3]-sigmatropic rearrangement and further Pummerer-type reactions of the resulting allyl sulfoxides. On the basis of the plausible reaction mechanism involving sulfonium salt intermediates, S-alkynylation and S-arylation were also accomplished.

History

Email Address of Submitting Author

s-yoshida.cb@tmd.ac.jp

Institution

Tokyo Medical and Dental University (TMDU)

Country

Japan

ORCID For Submitting Author

0000-0001-5888-9330

Declaration of Conflict of Interest

No conflict of interest

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