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Sterically Unprotected Nucleophilic Boron Cluster Reagents

preprint
submitted on 08.05.2019, 19:02 and posted on 09.05.2019, 16:01 by Xin Mu, Jonathan C. Axtell, Nicholas Bernier, Kent Kirlikovali, Dahee Jung, Alexander Umanzor, Kevin Qian, Xiangyang Chen, Katherine Bay, Monica Kirollos, Arnold L. Rheingold, K. N. Houk, Alexander Spokoyny
Herein, we demonstrate that the bench stable closo-hexaborate cluster anion can engage in a nucleophilic substitution reaction with a wide array of organic and main group electrophiles. The resulting molecules containing B‒C bonds can be further converted to tricoordinate boron species widely used in organic synthesis.

Funding

American Chemical Society Petroleum Research Fund (56562-DNI3)

NIH (R35GM124746)

Sloan Research Fellowship in Chemistry

Research Corporation for Science Advancement (RCSA), Cottrell Scholar Award

National Science Foundation (CHE-1764328)

History

Email Address of Submitting Author

spokoyny@chem.ucla.edu

Institution

UCLA

Country

USA

ORCID For Submitting Author

0000-0002-5683-6240

Declaration of Conflict of Interest

Authors declare no conflicts.

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