ChemRxiv
These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
1/1
4 files

Steric vs Electronic Effects: A New Look into Stability of Diastereomers, Conformers and Constitutional Isomers

preprint
submitted on 10.01.2021, 12:36 and posted on 11.01.2021, 13:29 by Sopanant Datta, Taweetham Limpanuparb
A quantum chemical investigation of the stability of compounds with identical formulas was carried out on 23 classes of halogenated compounds made of H, F, Cl, Br, I, C, N, P, O and S atoms. The prevalence of formula in which its Z configuration, gauche conformation and meta isomer are the most stable forms is calculated and discussed. The prevalence data shows that in compounds made of carbon backbones, the electronic effect is weaker than the steric effect. The electronic factor is more important as the backbone atoms are replaced with atoms on the right and upper part of the periodic table.

History

Email Address of Submitting Author

taweetham.lim@mahidol.edu

Institution

Mahidol University

Country

Thailand

ORCID For Submitting Author

0000-0002-8558-6199

Declaration of Conflict of Interest

no conflict of interest

Exports

Logo branding

Exports