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Step-by-Step Real Time Monitoring of a Catalytic Amination Reaction

preprint
submitted on 28.06.2019 and posted on 01.07.2019 by Gilian T. Thomas, Eric Janusson, Harmen S. Zijlstra, J Scott McIndoe
The multiple reaction monitoring mode of a triple quadrupole mass spectrometer is used to examine the Buchwald-Hartwig amination reaction at 0.1% catalyst loading in real-time using sequential addition of reagents to probe the individual steps in the cycle. This is a powerful new method for probing reactions under realistic conditions.

Funding

NSERC Discovery

History

Email Address of Submitting Author

mcindoe@uvic.ca

Institution

University of Victoria

Country

Canada

ORCID For Submitting Author

0000-0001-7073-5246

Declaration of Conflict of Interest

No conflict of interest

Version Notes

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