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Ibarlucea et al 2019 incl suppl matter.pdf (878.95 kB)

Single-Step Modified Electrodes for Vitamin C Monitoring in Sweat

submitted on 12.12.2019, 09:38 and posted on 18.12.2019, 12:30 by Bergoi Ibarlucea, Arnau Perez Roig, Dmitry Belyaev, Larysa Baraban, Gianaurelio Cuniberti
We demonstrate a flexible sensor for ascorbic acid detection in sweat based on single-step modified gold microelectrodes. The modification consists on the electrodeposition of alginate membrane with trapped CuO nanoparticles on top of the electrodes. The electrodes are fabricated at a thin polyimide support and the soft nature of the membrane can withstand mechanical stress far beyond the requirements for skin monitoring. We further show the efficient detection of ascorbic acid at the micromolar levels in both, a neutral buffer and acidic artificial sweat, at ultra-low applied potential (-5 mV). The effect of possible interfering species present in sweat is minimized, with no observable cross-reaction, thus maintaining a high degree of selectivity despite absence of enzymes in the fabrication scheme. This sensor is envisioned as a promising component of a wearable device for e.g. non-invasive monitoring of micronutrient loss through sweat.


AiF project F009438


Email Address of Submitting Author


TU Dresden



ORCID For Submitting Author


Declaration of Conflict of Interest

No conflict of interest