Simplified Computational Model for Generating Biological Networks
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A method to generate and simulate biological networks is discussed. An expanded Wooten-Winer-Weaire bond switching methods
is proposed which allows for
a distribution of node degrees in the network while conserving the mean average node degree.
The networks are characterised in terms of their polygon structure and assortativities (a measure
of local ordering). A wide range of experimental images are analysed and the underlying networks
quantified in an analogous manner. Limitations in obtaining the network structure are discussed.
A "network landscape" of the experimentally observed and simulated networks is constructed from the underlying metrics.
The enhanced bond switching algorithm is able to generate networks spanning the full range of experimental observations.
EPSRC Centre for Doctoral Training in Theory and Modelling in Chemical Sciences.
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