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20210215_PTCR_large_proteins_Fornelli.pdf (1.11 MB)

Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer

preprint
submitted on 16.02.2021, 02:57 and posted on 17.02.2021, 04:47 by Jake Kline, Christopher Mullen, Kenneth Durbin, Ryan Oates, Romain Huguet, John Syka, Luca Fornelli
We are submitting a manuscript describing the application of proton transfer charge reduction to increase the sequence coverage for proteins > 30 kDa using Orbitrap FTMS.

History

Email Address of Submitting Author

luca.fornelli@ou.edu

Institution

University of Oklahoma

Country

United States

ORCID For Submitting Author

0000-0001-6334-1046

Declaration of Conflict of Interest

C.M., J.E.P.S. and R.H. are employees of Thermo Scientific. K.R.D. is an employee of Proteinaceous, which commercializes software for the analysis of top-down mass spectrometry data.

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