These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
Selective Hydrodefluorination of Hexafluoropropene to Industrially Relevant Hydrofluoroolefins
preprintsubmitted on 10.02.2019, 17:59 and posted on 11.02.2019, 17:41 by Mark Crimmin, Andrew J. P. White, Nicholas A. Phillips
The selective hydrodefluorination of hexafluoropropene to HFO-1234ze and HFO-1234yf can be achieved by reaction with simple group 13 hydrides of the form EH3L (E = B, Al; L = SMe2, NMe3). The chemoselectivity varies depending on the nature of the group 13 element. A combination of experiments and DFT calculations show that competitive nucleophilic vinylic substitution and addition-elimination mechanisms involving hydroborated intermediates lead to complementary selectivities.