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ChemRxiv Ahmed.V2.pdf (577.85 kB)

Selective Electrosynthetic Hydrocarboxylation of alpha,beta-Unsaturated Olefins with Carbon Dioxide

preprint
revised on 08.04.2021, 11:31 and posted on 08.04.2021, 12:15 by Ahmed Sheta, Anas Alkayal, Andrei Malkov, Benjamin Buckley

Electrosynthetic hydrocarboxylation of alpha,beta-unsaturated olefins with excellent regioselectivity is reported. No sacrificial electrode is required and is thus amenable to a flow configuration. The products are purified by simple crystallisation. Synthesis of a precursor to ethosuximide, which contains an all-carbon quaternary centre, illustrates the potential of the process. Finally a robustness study has benchmarked the process for future users.

Funding

Underpinning Multi-User Equipment

Engineering and Physical Sciences Research Council

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History

Email Address of Submitting Author

b.r.buckley@lboro.ac.uk

Institution

Loughborough University

Country

UK

ORCID For Submitting Author

0000-0002-8028-0828

Declaration of Conflict of Interest

None

Version Notes

Version 2.0

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