These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
Preprints are manuscripts made publicly available before they have been submitted for formal peer review and publication. They might contain new research findings or data. Preprints can be a draft or final version of an author's research but must not have been accepted for publication at the time of submission.
submitted on 17.08.2020 and posted on 17.08.2020by Shoji Iwabuchi, Ibuki Kawamata, Satoshi Murata, Shin-ichiro Nomura
Here, we report on the design and function of a membrane nanopore through a DNA origami
square tube with a cross-section of 100 nm2
. When the nanopore is added onto the giant
vesicle membrane, the permeation of hydrophilic fluorescent molecules was observed. It can
be sealed by the existence of the four specific single strand DNAs. A controllable artificial
nanopore should help to communicate the vesicle components with their environment