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Reversing Conventional Site-Selectivity in C(sp3)-H Bond Activation

preprint
submitted on 03.09.2018 and posted on 05.09.2018 by guoqin xia, pritha verma, jiang weng, Luoyan Liu, Ziqiang Li, jin-quan yu
Distal C(sp3)–H bonds of aliphatic alcohols are preferentially activated over proximate C(sp3)–H bonds through a combination of directing group design and ligand acceleration.

History

Email Address of Submitting Author

yu200@scripps.edu

Institution

The Scripps Research Institute

Country

USA

ORCID For Submitting Author

0000-0003-3560-5774

Declaration of Conflict of Interest

we declare no conflicts of interests.

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