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Preparation and Synthetic Applicability of Novel Imidazole-Containing Cyclic Iodonium Salts

preprint
submitted on 22.02.2021, 19:40 and posted on 23.02.2021, 11:21 by Antonkin Nikita, Yulia Vlasenko, Akira Yoshimura, Vladimir Smirnov, Tatyana Borodina, Viktor Zhdankin, Mekhman Yusubov, Alexandr Shafir, Pavel Postnikov

The novel approach to the preparation of imidazole-substituted cyclic iodonium salts has been developed via oxidative cyclization of 1-phenyl-5-iodoimidazole using cheap and available Oxone®/H2SO4 oxidative system. The structure of newly prepared compounds has been proved by X-ray monocrystal diffractometry revealing the characteristic surface features for cyclic iodonium salts. The prepared compounds demonstrated the high reactivity in the heterocyclization reactions with elemental sulfur affording benzo[5,1-b]imidazothiazoles with good yields.

Funding

Russian Science Foundation (№ 17-73-20066)

Russian Foundation of Basic Research (№ 20-33-90007)

Spain’s MINECO (CTQ2017-86936-P)

AGAUR (2017 SGR 01051)

History

Email Address of Submitting Author

postnikov@tpu.ru

Institution

Tomsk Polytechnic University

Country

Russian Federation

ORCID For Submitting Author

0000-0001-9713-1290

Declaration of Conflict of Interest

The authors declare the absence of any conflict of interest

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