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Preparation and Synthetic Applicability of Novel Imidazole-Containing Cyclic Iodonium Salts

submitted on 22.02.2021, 19:40 and posted on 23.02.2021, 11:21 by Antonkin Nikita, Yulia Vlasenko, Akira Yoshimura, Vladimir Smirnov, Tatyana Borodina, Viktor Zhdankin, Mekhman Yusubov, Alexandr Shafir, Pavel Postnikov

The novel approach to the preparation of imidazole-substituted cyclic iodonium salts has been developed via oxidative cyclization of 1-phenyl-5-iodoimidazole using cheap and available Oxone®/H2SO4 oxidative system. The structure of newly prepared compounds has been proved by X-ray monocrystal diffractometry revealing the characteristic surface features for cyclic iodonium salts. The prepared compounds demonstrated the high reactivity in the heterocyclization reactions with elemental sulfur affording benzo[5,1-b]imidazothiazoles with good yields.


Russian Science Foundation (№ 17-73-20066)

Russian Foundation of Basic Research (№ 20-33-90007)

Spain’s MINECO (CTQ2017-86936-P)

AGAUR (2017 SGR 01051)


Email Address of Submitting Author


Tomsk Polytechnic University


Russian Federation

ORCID For Submitting Author


Declaration of Conflict of Interest

The authors declare the absence of any conflict of interest