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Pine Rosin as a Toxic Cannabis Extract Adulterant

preprint
submitted on 16.01.2020 and posted on 20.01.2020 by Jiries Meehan-Atrash, Robert Strongin
Pine rosin (colophony) has been identified as a new adulterant in cannabis oil for vaping. Its inhalation toxicity is a significant health concern. For example, pine rosin fumes are released during soldering, and have been cited as a causative agent of occupational asthma. Symptoms also include desquamation of bronchial epithelium, which has been observed in EVALI patients. The sample analyzed herein also contains medium chain triglycerides and oleamide, the latter of which is found in the synthetic marijuana product Spice, or K2. A combination of NMR and HPLC-ESIMS was used to unambiguously identify major pine rosin ingredients such as abietic and other resin acids. Comparison to commercial samples of pure pine rosin confirmed the assignment.

Funding

NATIONAL INSTITUTES OF HEALTH (NIH)

United States Department of Health and Human Services

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US FOOD AND DRUG ADMINISTRATION

History

Email Address of Submitting Author

strongin@pdx.edu

Institution

Portland State University

Country

USA

ORCID For Submitting Author

0000-0003-3777-8492

Declaration of Conflict of Interest

No conflict of interest

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