ChemRxiv
These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
1/1
0/0

Photoredox-Catalyzed Intermolecular Radical Addition to Allenamides: A Complementary Approach to Conjugated N-Acyliminium Formation.

preprint
submitted on 05.09.2019 and posted on 07.09.2019 by Kayode Koleoso, Matthew Turner, Felix Plasser, Marc Kimber

An intermolecular radical addition, using photoredox catalysis, to allenamides is reported. This transformation synthesizes N-acyl-N’-aryl-N,N’-allylaminals, and proceeds by a conjugated N-acyliminium intermediate, that previously, has only been generated by electrophilic activation methods. The radical adds to the central carbon of the allene giving a conjugated N-acyliminium, that undergoes nucleophilic addition by arlyamines and alcohols.

History

Email Address of Submitting Author

M.C.Kimber@lboro.ac.uk

Institution

Loughborough University

Country

UK

ORCID For Submitting Author

0000-0003-2943-1974

Declaration of Conflict of Interest

No conflict of interest

Exports

Logo branding

Exports