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Spatially Controlled Glycocalyx Engineering for Growth Factor Patterning in Embryoid Bodies

preprint
revised on 18.08.2020 and posted on 19.08.2020 by Matthew R. Naticchia, Logan K. Laubach, honigfort Daniel J., purcell Sean C., Kamil Godula
Cell surface engineering with synthetic glycomimetic co-receptors for FGF2 was used to establish gradients of stem cells with enhanced FGF2 affinity in embryoid bodies (EBs). Gradient shape was controlled by pre-assembly of glycomimetics into nanoscale vesicles with tunable dimensions and EB penetrance.

History

Email Address of Submitting Author

kgodula@ucsd.edu

Institution

UCSD

Country

USA

ORCID For Submitting Author

0000-0001-7953-4619

Declaration of Conflict of Interest

the authors have no conflicts of interest

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