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Spatially Controlled Glycocalyx Engineering for Growth Factor Patterning in Embryoid Bodies

preprint
revised on 18.08.2020, 14:29 and posted on 19.08.2020, 09:36 by Matthew R. Naticchia, Logan K. Laubach, honigfort Daniel J., purcell Sean C., Kamil Godula
Cell surface engineering with synthetic glycomimetic co-receptors for FGF2 was used to establish gradients of stem cells with enhanced FGF2 affinity in embryoid bodies (EBs). Gradient shape was controlled by pre-assembly of glycomimetics into nanoscale vesicles with tunable dimensions and EB penetrance.

History

Email Address of Submitting Author

kgodula@ucsd.edu

Institution

UCSD

Country

USA

ORCID For Submitting Author

0000-0001-7953-4619

Declaration of Conflict of Interest

the authors have no conflicts of interest

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