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Gerz-CuSynt21.pdf (954.77 kB)

One-Pot Synthesis and Characterization of Biomimetic Copper(I) Complexes

preprint
submitted on 07.02.2021, 18:16 and posted on 09.02.2021, 04:50 by Isabelle Gerz, Chiara Negri, David Wragg, Sigurd Øien-Ødegaard, Mats Tilset, Unni Olsbye, Mohamed Amedjkouh
A modular one-pot synthesis yielding tetracoordinated-N,N,N,N-copper(I) complexes bearing imine and diimine ligands was developed. Copper aids the condensation of a pyridine or imidazole carbaldehyde with a biphenyl amine and even stabilizes labile ligands. Tetradentate and bidentate ligands were formed, the latter forming homoleptic CuL2 complexes. The identity and purity of the compounds were assessed by NMR, elemental analysis and mass spectrometry. The interconversion of different species in solution was studied by variable temperature NMR. The complexes aim to mimic the histidine copper brace of lytic polysaccharide monooxygenases (LPMOs) and bond lengths obtained from XAS and single crystal XRD for the complexes were compared to reported photoreduced LPMOs.

Funding

Norges forskningsråd

History

Email Address of Submitting Author

mamou@kjemi.uio.no

Institution

University of Oslo, Chemistry Department

Country

Norway

ORCID For Submitting Author

0000-0002-2707-7767

Declaration of Conflict of Interest

None

Exports