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submitted on 20.03.2020 and posted on 23.03.2020by Rosie Somerville, Carlota Odena, Marc Obst, Nilay Hazari, Kathrin Hopmann, Ruben Martin
ABSTRACT: Although the catalytic carboxylation of unactivated alkyl electrophiles has reached remarkable levels of sophistication, the intermediacy of (phenanthroline)Ni(I)-alkyl species – complexes proposed in numerous Ni-catalyzed reductive cross-coupling reactions – has been subject to speculation. Herein, we report the synthesis of such elusive (phenanthroline)Ni(I) species and their reactivity with CO2, allowing us to address a long-standing challenge related to metal-catalyzed carboxylation reactions.