ChemRxiv
These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
1/1
0/0

Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging

preprint
submitted on 18.05.2020 and posted on 19.05.2020 by Chenchen LIU, Xiuxia Wang, Junkai Liu, Qiang Yue, Jacky W. Y. Lam, Liang Luo, Ben Zhong Tang
A novel AIEgen named TBL was designed based on the classic CL emitter luminol. The NIR CL emission of TBL dots could penetrate through 3 cm-thick pork ham, which is much better than NIR fluorescence and blue CL emission. Moreover, the successful differentiation of tumor and normal tissue makes this system promising for CL-guided tumor diagnosis and surgery.

Funding

National Science Foundation of China (21788102)

Research Grants Council of Hong Kong (N_HKUT609/19, C6009-17G and A-HKUST 605/16)

Innovation and Technology Commission (ITC-CNERC14SC01 and ITCPD/17-9)

Ming Wai Lau Centre for Reparative Medicine, Karolinska Institute (MWLC19Sc02)

National Basic Research Plan of China (2018YFA0208903)

History

Email Address of Submitting Author

cliucg@connect.ust.hk

Institution

The Hong Kong University of Science and Technology

Country

China

ORCID For Submitting Author

0000-0001-9488-0675

Declaration of Conflict of Interest

No

Exports

Logo branding

Exports