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Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging
preprintsubmitted on 18.05.2020, 15:19 and posted on 19.05.2020, 12:10 by Chenchen LIU, Xiuxia Wang, Junkai Liu, Qiang Yue, Jacky W. Y. Lam, Liang Luo, Ben Zhong Tang
A novel AIEgen named TBL was designed based on the classic CL emitter luminol. The NIR CL emission of TBL dots could penetrate through 3 cm-thick pork ham, which is much better than NIR fluorescence and blue CL emission. Moreover, the successful differentiation of tumor and normal tissue makes this system promising for CL-guided tumor diagnosis and surgery.