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Natural Flavonoids as Superior Reagents for Separation of Clinically Important Zr Radionuclides

preprint
submitted on 24.10.2019 and posted on 28.10.2019 by Kalpita Ghosh, Nabanita Naskar, Dibyasree Choudhury, Susanta Lahiri
This paper exploits the affinity of bio-flavonoid hesperidin, isolated from orangepeel, towards the separation of clinically important 88Zr radionuclide from high energy proton bombarded yttrium target. The extraction of Zr with hesperidin was studied by solid-liquid extraction (SLX) technique over a wide pH range. The advantage of hesperidin is that it acts as separating agent as well as free-radical scavenging agent upon injection of the radionuclidehesperidin complex in-vivo. The stability of isolated hesperidin under strong radiation field was also studied. The selectivity of the bio-flavonoid towards 88Zr was maximum at pH=4 where in >78% Zr was extracted with <1% contamination from bulk yttrium target.

History

Email Address of Submitting Author

susanta.lahiri.sinp@gmail.com

Institution

Saha Institute of Nuclear Physics

Country

India

ORCID For Submitting Author

0000-0003-0055-1569

Declaration of Conflict of Interest

No conflict of interest

Version Notes

This is preliminary data

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