These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
2 files

Natural Flavonoids as Superior Reagents for Separation of Clinically Important Zr Radionuclides

submitted on 24.10.2019, 17:31 and posted on 28.10.2019, 21:16 by Kalpita Ghosh, Nabanita Naskar, Dibyasree Choudhury, Susanta Lahiri
This paper exploits the affinity of bio-flavonoid hesperidin, isolated from orangepeel, towards the separation of clinically important 88Zr radionuclide from high energy proton bombarded yttrium target. The extraction of Zr with hesperidin was studied by solid-liquid extraction (SLX) technique over a wide pH range. The advantage of hesperidin is that it acts as separating agent as well as free-radical scavenging agent upon injection of the radionuclidehesperidin complex in-vivo. The stability of isolated hesperidin under strong radiation field was also studied. The selectivity of the bio-flavonoid towards 88Zr was maximum at pH=4 where in >78% Zr was extracted with <1% contamination from bulk yttrium target.


Email Address of Submitting Author


Saha Institute of Nuclear Physics



ORCID For Submitting Author


Declaration of Conflict of Interest

No conflict of interest

Version Notes

This is preliminary data


Logo branding