Nanohoop Rotaxane Design to Enhance Selectivity of Reaction Based Probes: A Proof of Principle Study
Preprints are manuscripts made publicly available before they have been submitted for formal peer review and publication. They might contain new research findings or data. Preprints can be a draft or final version of an author's research but must not have been accepted for publication at the time of submission.
A novel fluorescent probe design based on the interlocking of a reactive thread in a rigid nanohoop fluorophore is reported. This rotaxane design leads to size-selective sensing of thiolates in organic solution. More broadly, the work suggests the promise of mechanical interlocking to enhance the selectivity of reaction-based probes.
Chemical Tools for Delivery and Detection of Biological Hydrogen Sulfide
National Institute of General Medical SciencesFind out more...