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Monitoring Polymer-Assisted Mechanochemical Cocrystallisation Through in Situ X-Ray Powder Diffraction

preprint
submitted on 17.03.2020 and posted on 19.03.2020 by Luzia S. Germann, Sebastian T. Emmerling, Manuel Wilke, Robert E. Dinnebier, Mariarosa Moneghini, Dritan Hasa
Time-resolved mechanochemical cocrystallisation studies have so-far focused solely on neat and liquid-assisted grinding. Here, we report the monitoring of polymer-assisted grinding reactions using in situ X-ray powder diffraction, revealing that reaction rate is almost double compared to neat grinding and independent of the molecular weight and amount of used polymer additives.

Funding

Swiss National Science Foundation (P2SKP2_187638)

University of Trieste (FRA 2020)

History

Email Address of Submitting Author

Luzia.germann@gmail.com

Institution

Max Planck Institute for Solid State Research

Country

Germany

ORCID For Submitting Author

0000-0003-1760-5842

Declaration of Conflict of Interest

no conflict of interest

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