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submitted on 07.09.2018 and posted on 07.09.2018by Thanh Vinh Nguyen, Uyen P. N. Tran, Giulia Oss, Martin Breugst, Eric Detmar, Kevin Liyanto
The carbonyl-olefin metathesis reaction is a
synthetically valuable transformation that could facilitate rapid functional
group interconversion and construction of new organic structures. Herein we
demonstrate that elemental iodine, a very simple and mild catalyst, can
efficiently promote this chemical transformation under mild reaction conditions
with excellent outcomes. Our mechanistic studies revealed intriguing aspects of
iodine activation mode that could change the previously established perception
of catalyst and substrate design for the carbonyl-olefin metathesis reaction.