ORF10: Molecular Insights into the Contagious Nature of Pandemic Novel Coronavirus 2019-nCoV

12 May 2020, Version 3
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

This article stems from the author's observations that ORF10, a protein with no sequence and structural conservation, provides with a high number of potentially immunogenic, promiscuous epitopes. With high degree of epitope conservation across CTL and HTL epitopes of ORF10, its existence in the 2019-nCoV genome is largely seen as particularly contributing to the highly contagious nature of this virus.

Keywords

Immunoinformatics
nCoV-2019
SARS coronavirus
SARS-CoV2

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