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Mikania Mikrantha Leaf Extract Mediated Biogenic Synthesis of Magnetic Iron Oxide Nanoparticles: Characterization and Its Antimicrobial Activity Study

submitted on 07.11.2020, 13:25 and posted on 09.11.2020, 10:50 by Aayushi Biswas, Vanlalveni Chhangte, R. Lalfakzuala, Soumitra Nath, Samuel Lalthazuala Rokhum

With an aim to introduce a new highly potent antimicrobial nanoparticles using an environment-friendly route, he present work reports the green synthesis of iron oxide nanoparticles (Fe3O4NPs) utilizing Mikania mikrantha leaf extract and its application as efficient antimicrobial agent. The green Fe3O4NPs have been described by X-beam diffraction (XRD), Ultraviolet-Visible (UV-Vis) spectroscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Fourier Transform-Infra Red (FT-IR) investigation. The TEM image shows the rhomboidal Fe3O4NPs with average mean sizes 20.27 nm. The FT-IR investigation proved Fe3O4NPs have been balanced out through the associations of steroids, terpenoids, flavonoids, phenyl propanoids, phenolic acids and proteins present in the leaf extract. The synthesized Fe3O4NPs shows a very high antibacterial and antifungal property against 5 bacterial strains such as Bacillus cereus, Acinetobacter johnsonii, Pseudomonas aeruginosa, Achromobacter spanius and Chromobacterium pseudoviolaceum strain, and 4 fungal strains (Aspergillus niger, Penicillium citirinum, Fusarium oxysporium, and Candida albicans). The green synthesized iron oxide nanoparticles can interfere metabolic activities of microorganisms which determine its antimicrobial properties and could bring a promising application in the fields of medicine.


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