These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
Microfibrous extracellular matrix enhances in vitro modeling of the liver hepatocytes by modulating metabolism and integrin expression
preprintsubmitted on 27.01.2020, 19:18 and posted on 31.01.2020, 17:47 by Tianjiao Huang, Curtis G. Jones, Jay H. Chung, Chengpeng Chen
A microfibrous ECM fabricated by electrospinning silk fibroin can modulate the energy metabolism, amino acids bioavailability, and integrins expression in hepatocytes, making the cells more physiologically relevant.