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Microfibrous extracellular matrix enhances in vitro modeling of the liver hepatocytes by modulating metabolism and integrin expression

preprint
submitted on 27.01.2020 and posted on 31.01.2020 by Tianjiao Huang, Curtis G. Jones, Jay H. Chung, Chengpeng Chen
A microfibrous ECM fabricated by electrospinning silk fibroin can modulate the energy metabolism, amino acids bioavailability, and integrins expression in hepatocytes, making the cells more physiologically relevant.

Funding

Intramural Research Program of National Heart Lung and Blood Institute, National Institutes of Health

UMBC startup funding

History

Email Address of Submitting Author

cpchen@umbc.edu

Institution

University of Maryland Baltimore County

Country

USA

ORCID For Submitting Author

0000-0001-7754-344X

Declaration of Conflict of Interest

N/A

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