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Merging Chemoenzymatic and Radical-Based Retrosynthetic Logic For Rapid and Modular Synthesis of Oxidized Meroterpenoids

preprint
submitted on 21.02.2019 and posted on 21.02.2019 by Jian Li, Fuzhuo Li, Emma King-Smith, Hans Renata
We report a modular approach to access a range of oxidized meroterpenoids using a novel hybrid synthetic strategy involving enzymatic hydroxylation and radical based transformations.

Funding

Biocatalytic C -H Functionalization Logic in the Chemoenzymatic Synthesis of Therapeutic Natural Products

National Institute of General Medical Sciences

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History

Email Address of Submitting Author

hrenata@scripps.edu

Institution

The Scripps Research Institute

Country

USA

ORCID For Submitting Author

0000-0003-2468-2328

Declaration of Conflict of Interest

No conflict of interest

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