In-Silico Interaction of Hydroxychloroquine Drug with Various Proteins of Coronavirus (SARS-CoV-2): A Computational Approaches to Combat COVID-19
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In silico docking study showed that hydroxychloroquine drug interactions with SARS-CoV2 show a higher binding affinity with spike glycoprotein and PLPRO protein compared to protein envelopes that could be ladder for potential targeting and synthesizing of another aniviral drug. In silico methods used in this study, the efficacy of a wide variety of repositioned and/or novel drug candidates could also be tested prior to clinical evaluation.