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Henderson Hasselbalch Relationship and Weak Acid Titration

preprint
submitted on 11.06.2019 and posted on 12.06.2019 by Marc Blétry
Henderson-Hasselbalch relation is generally the simplified theoretical framework used to introduce students to acid-base titration. However, it is not always valid and its limitations should be made clear to chemistry students. The appropriate parameter to evaluate its validity is K a /C 0 , in connection with Ostwald dilution law. For more advanced students, it is possible to deduce analytical expressions that always fit accurately acid-base titrations and allow an evaluation of Henderson Hasselbalch relation. Gran plot appears as a particularly sensitive technique to the breakdown of Henderson Hasselbalch relation.

History

Email Address of Submitting Author

bletry@icmpe.cnrs.fr

Institution

ICMPE-UPEC

Country

France

ORCID For Submitting Author

0000-0003-2509-9847

Declaration of Conflict of Interest

No conflict of interest

Version Notes

This is the first and - a priori - final version of the paper.

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