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H2O as the Sole Hydrogen Source for Ni-Catalyzed Reduction of Alkenes

preprint
submitted on 02.05.2019 and posted on 03.05.2019 by Yichen Wu, Tao liu, Dongping Chen, Daoming Wang, Peng Wang
Herein, we reported a nickel catalyzed hydrogenation of alkenes with water as the sole hydrogen source. Employing Zn as reductant and water as solvent in the presence of a catalytic amount of nickel catalyst led to direct hydrogenation of a series of electron-rich and electron-deficient alkenes in high yields. This protocol features unprecedented heterocycle and functional group tolerance under facile and mild conditions. Selective hydrogenation of the substrates containing additional reducible functionalities, such as alkenyl, alkynyl, chloride, ketone, and benzyl group etc, was also realized.

Funding

Shanghai Institute of Organic Chemistry

History

Email Address of Submitting Author

pengwang@sioc.ac.cn

Institution

Shanghai Institute of Organic Chemistry

Country

China

ORCID For Submitting Author

0000-0002-6442-3008

Declaration of Conflict of Interest

The authors declare no competing financial interest.

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