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Golden Opportunity: A Clickable Azide-Functionalized [Au25(SR)18]-Nanocluster Platform for Interfacial Surface Modifications

preprint
submitted on 14.05.2019 and posted on 16.05.2019 by Praveen Gunawardene, John F. Corrigan, Mark Workentin
Ultrasmall atomically precise monolayer-protected gold thiolate nanoclusters are an intensely researched nanomaterial framework, but there is a lack of a system that can be directly synthesized and undergo interfacial surface chemistry. We report an [Au25(SCH2CH2-p-C6H4-N3)18]- nanocluster platform with azide moieties appended onto each surface ligand. The structure of this surface reactive cluster has been confirmed by single-crystal X-ray crystallography, mass spectrometry and UV-Vis, IR and NMR spectroscopies. We show that all surface azide moieties are amenable to cluster-surface strain-promoted alkyne-azide cycloaddition (CS-SPAAC) chemistry with a strained cyclooctyne, opening this as a new platform to allow functional, post-assembly surface modifications to this very prominent nanocluster.

History

Email Address of Submitting Author

mworkent@uwo.ca

Institution

The University of Western Ontario

Country

Canada

ORCID For Submitting Author

0000-0001-8517-6483

Declaration of Conflict of Interest

none

Version Notes

submitted version

Exports