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Generic High-Capacity Electrochemical Capture and Release of Proteins by Polyelectrolyte Brushes

preprint
submitted on 23.03.2020 and posted on 23.03.2020 by Gustav Ferrand-Drake del Castillo, Zeynep Adali, Rebekah L. N. Hailes, Kunli Xiong, Andreas Dahlin

We present a polyelectrolyte brush electrode with high-capacity for protein immobilization that captures and releases proteins by an electrochemical potential. Central to our concept is the use of polyelectrolyte brushes that switch reversibly by electrochemistry. Our electrode enables high-fidelity control of protein species in space and time. We predict several application areas for this technology; for instance in protein separation and in biomedical devices.

History

Email Address of Submitting Author

gustavd@chalmers.se

Institution

Chalmers University of Technology, Chemistry and Chemical Engineering

Country

Sweden

ORCID For Submitting Author

0000-0002-7737-1796

Declaration of Conflict of Interest

GFD and AD have applied for a patent of the technology.

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