Generic High-Capacity Electrochemical Capture and Release of Proteins by Polyelectrolyte Brushes

We present a polyelectrolyte brush electrode with high-capacity for protein immobilization that captures and releases proteins by an electrochemical potential. Central to our concept is the use of polyelectrolyte brushes that switch reversibly by electrochemistry. Our electrode enables high-fidelity control of protein species in space and time. We predict several application areas for this technology; for instance in protein separation and in biomedical devices.