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Formal Syntheses of Dictyodendrins B, C, and E by a Multi-substituted Indole Synthesis

preprint
submitted on 01.04.2021, 12:08 and posted on 02.04.2021, 12:59 by AKira Kabuki, Junichiro Yamaguchi
The dictyodendrins are a family of marine alkaloids, which possess a highly substituted pyrrolo[2,3-c]carbazole core. This core structure can be regarded as a multi-substituted indole and aniline moiety. To achieve a concise synthesis of dictyodendrins, we planned to capitalize on our previously developed multi-substituted indole synthesis. By using this method along with two C–H functionalizations, formal syntheses of dictyodendrin B, C, and E were achieved.

Funding

JP19H02726

Komozaka Chromatin Atlas Project

Japan Science and Technology Agency

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History

Email Address of Submitting Author

junyamaguchi@waseda.jp

Institution

Waseda University

Country

Japan

ORCID For Submitting Author

0000-0002-3896-5882

Declaration of Conflict of Interest

No competing financial interests have been declared.

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