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Evolution of N-Heterocycle-substituted Iodoarenes (NHIAs) to efficient Organocatalysts in Iodine(I/III)-mediated Oxidative Transformations

preprint
submitted on 10.10.2019, 13:25 and posted on 16.10.2019, 05:59 by Andreas Boelke, Boris Nachtsheim
We herein describe the development of N-heterocycle-stabilized iodoarenes (NHAIs) as oxidation catalysts for oxidative C-X-bond forming reactions. Modification of the N-heterocycle as stabilizing donor in combination with an additional ortho-methoxylation of the iodoarene finally gives organocatalysts that can be applied in the alpha-oxytosylation of ketones even with catalyst loadings as low as 1 mol%.

Funding

Fonds der Chemischen Industrie

History

Email Address of Submitting Author

nachtsheim@uni-bremen.de

Institution

University of Bremen

Country

Germany

ORCID For Submitting Author

0000-0002-3759-2770

Declaration of Conflict of Interest

no conflict of interest

Version Notes

initial submission

Exports