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Ester Transfer Reaction of Aromatic Esters with Haloarenes and Arenols by a Nickel Catalyst

submitted on 12.01.2020, 02:42 and posted on 13.01.2020, 12:30 by Ryota Isshiki, Naomi Inayama, Kei Muto, Junichiro Yamaguchi
A catalytic ester transfer reaction of aromatic esters with aryl halides/arenols was developed. The present reaction can transfer an ester functional group from certain aromatic esters to haloarenes. This ester transfer reaction involves two oxidative additions­­— one from the C–C bond of the aromatic ester and one from the C–halogen bond of haloarenes— onto a nickel catalyst. The utilization of a Ni/dcypt catalyst capable of cleaving both chemical bonds was a key for the reaction progress. Furthermore, naphthol-based aryl electrophiles were also applicable to the catalytic system via C–O bond activation.


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Waseda University



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Declaration of Conflict of Interest

No competing financial interests have been declared.