These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.

Engineering New Defective Phases of UiO Family Metal-Organic Frameworks with Water

submitted on 06.11.2018 and posted on 07.11.2018 by Francesca Firth, Matthew Cliffe, Diana Vulpe, Peyman Moghadam, David Fairen-jimenez, ben slater, Clare P. Grey
As defects significantly affect the properties of metal-organic frameworks (MOFs)–from changing their mechanical properties to enhancing their catalytic ability–obtaining synthetic control over defects is essential to tuning the effects on the properties of the MOF. Previous work has shown that synthesis temperature and the identity and concentration of modulating acid are critical factors in determining the nature and distribution of defects in the UiO family of MOFs. In this paper we demonstrate that the amount of water in the reaction mixture in the synthesis of UiO family MOFs is an equally important factor, as it controls the phase which forms for both UiO-67(Hf)
and UiO-66(Hf) (F4BDC). We use this new understanding of the importance of water to develop a new route to the stable defect-ordered hcp UiO-66(Hf) phase, demonstrating the effectiveness of this method of defect-engineering in the rational design of MOFs. The insights provided by this
investigation open up the possibility of harnessing defects to produce new phases and dimensionalities of other MOFs, including nanosheets, for a variety of applications such as MOF-based membranes.


EPSRC, Royal Society, European Research Council


Email Address of Submitting Author


University of Cambridge, Department of Chemistry



ORCID For Submitting Author


Declaration of Conflict of Interest

There are no conflicts to declare.

Version Notes

Original Version; uploaded prior to review