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Enantiomeric Excess Dependent Splitting of NMR Signal Through Co-Ligand Dynamic Exchange in a Coordination Complex
preprintsubmitted on 27.04.2020, 07:55 and posted on 28.04.2020, 05:57 by Kazuyoshi Takimoto, Shinsuke Ishihara, Jan Labuta, Václav Březina, Daniel Payne, Katsuhiko Ariga, Jonathan P. Hill, Masato Sumita, Shigeki Mori, Hisako Sato
A coordination complex (L·2Zn·3C), where L is a prochiral ligand and C is an exchangeable acetate co-ligand, exhibits symmetrical splitting of 1H-NMR resonances due to L, which is proportional to the enantiomeric excess (ee) of a chiral guest co-ligand, 2-phenoxypropionic acid (PPA). The NMR resonances remain split even in dilute solution due to the high stability of complex with chiral guest.