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Takimoto_ChemRxiv_20200427.pdf (8.05 MB)

Enantiomeric Excess Dependent Splitting of NMR Signal Through Co-Ligand Dynamic Exchange in a Coordination Complex

submitted on 27.04.2020, 07:55 and posted on 28.04.2020, 05:57 by Kazuyoshi Takimoto, Shinsuke Ishihara, Jan Labuta, Václav Březina, Daniel Payne, Katsuhiko Ariga, Jonathan P. Hill, Masato Sumita, Shigeki Mori, Hisako Sato
A coordination complex (L·2Zn·3C), where L is a prochiral ligand and C is an exchangeable acetate co-ligand, exhibits symmetrical splitting of 1H-NMR resonances due to L, which is proportional to the enantiomeric excess (ee) of a chiral guest co-ligand, 2-phenoxypropionic acid (PPA). The NMR resonances remain split even in dilute solution due to the high stability of complex with chiral guest.


JSPS KAKENHI Grant No. JP16H06518 (Coordination Asymmetry), and Grant No. 19K05229


Email Address of Submitting Author


National Institute for Materials Science



ORCID For Submitting Author


Declaration of Conflict of Interest

There is no conflict of interest.

Version Notes

This is the first version