Dynamics of Individual Molecular Shuttles Under Mechanical Force

10 October 2018, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Here, we exploit the high force (0.1 pN), spatial (1 nm) and temporal (1 kHz) resolutions of optical tweezers to quantify and control mechanically the real-time kinetics of individual synthetic molecular shuttles operating at near-physiological conditions, for several hundreds of switching cycles, near equilibrium conditions.

Keywords

rotaxane
Molecular shuttles
optical tweezers
dynamics
Brownian motion
single-molecule measurements

Supplementary materials

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Dynamics of individual molecular shuttles Supplementary Materials chemRxiv
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