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Dual Ligand-Enabled Nondirected C–H Cyanation of Arenes
preprintsubmitted on 09.10.2018, 11:07 and posted on 10.10.2018, 14:11 by Hao Chen, Arup Mondal, Manuel van Gemmeren
Aromatic nitriles are key structural units in organic chemistry and thus highly attractive targets for C–H activation. Herein the development of an arene-limited, nondirected C–H cyanation based on the use of two complementary ligands is reported. The reaction enables the cyanation of arenes by C–H activation in the absence of directing groups and is thus complementary to established approaches.
Read the published paper
in ACS Catalysis