Direct Measurement of the Visible to UV Photodissociation Processes for the PhotoCORM TryptoCORM

23 December 2019, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We apply laser photodissociation spectroscopy in the gas phase to TryptoCORM, a known photoCORM that has been shown to destroy Escherichia coli upon visible-light activation. Our experiments allow us to fully map TryptoCORM’s photochemistry across a wide wavelength range by using novel laser-interfaced mass spectrometry (LIMS). We complement these measurements with Cryogenic Ion Vibrational Spectroscopy (CIVS), to structurally characterise gaseous TryptoCORM.

Keywords

PhotoCORM
TryptoCORM
Metal Carbonyl
Photochemistry
Photodissociation
prodrugs
photoactivated pharmaceutical

Supplementary materials

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