Differences in the Performance of Allyl Based Palladium Precatalysts for Suzuki-Miyaura Reactions

We evaluate the activity of different allyl-based precatalysts in Suzuki-Miyaura reactions as the ancillary ligand (NHC or phosphine), reaction conditions, and substrates are varied. In some cases, we connect relative activity to both the mechanism of activation and the prevalence of the formation of inactive palladium(I) dimers.