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Herein, we have successfully unveiled a simple and
inexpensive removable aliphatic template as an effective DG template in
promoting remote meta-C−H olefination of arenes for the first time. Remarkably,
the template was achieved in excellent yields in just two steps and without
column chromatography purification. The protocol is an efficient, economical
and practical approach in achieving meta-C−H olefination in good to
excellent isolated yields and high levels of meta-selectivity under mild
conditions. A wide variety of substituted arenes and olefin coupling partners
are well tolerated in this reaction. Moreover, the aliphatic template is found
to be advantageous due to its easy synthesis, easy installation/removal, and
recycle. We believe that this strategy offers new opportunities for the future
development of new DG templates to promote site-selective C−H