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Designing of Cytotoxic and Helper T Cell Epitope Map Provides Insights into the Highly Contagious Nature of the Pandemic Novel Coronavirus SARS-CoV2
preprintsubmitted on 07.05.2020, 03:58 and posted on 11.05.2020, 05:17 by Seema Mishra
This study provides key insights into the contagious nature of SARS-CoV2 through analyses of T cell epitopes designed from SARS-CoV2 proteome. All top-scoring cytotoxic T cell epitopes from ORF1ab and helper T cell epitopes identified from all proteins were utilized to provide crucial insights into its pathogenesis. These T cell epitopes can be used as prophylactic or therapeutic multi-subunit vaccine or as diagnostic tools.