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Borova POx-polyperoxide crosslinking first submitted manuscript.pdf (3.61 MB)

Crosslinking of Hydrophilic Polymers Using Polyperoxides

submitted on 11.05.2020, 07:47 and posted on 12.05.2020, 12:17 by Solomiia Borova, Philipp Stahlhut, Victor Tokarev, Robert Luxenhofer

Hydrogels that can mimic mechanical properties and functions of biological tissue have attracted great interest in tissue engineering and biofabrication. In these fields, new materials and approaches to prepare hydrogels without using toxic starting materials or materials that decompose into toxic compounds remain to be sought after. Here, we report the crosslinking of commercial, unfunctionalized hydrophilic poly(2-ethyl-2-oxazoline) using peroxide copolymers in their melt. The influence of temperature, peroxide copolymer concentration and duration of the crosslinking process has been investigated. The method allows to create hydrogels from unfunctionalized polymers in their melt and to control the mechanical properties of the resulting materials. The design of hydrogels with a suitable mechanical performance is of crucial importance in many existing and potential applications of soft materials, including medical applications.


Deutsche Forschungsgemeinschaft


Email Address of Submitting Author


Julius-Maximilians-Universität Würzburg



ORCID For Submitting Author


Declaration of Conflict of Interest

No conflicts of interests

Version Notes

First version submitted for peer review



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in Colloid and Polymer Science

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