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Correlation between Yield and Reduced Mass of Raw Materials in Enzymatic Reactions.pdf (581.59 kB)

Correlation Between Yield and Reduced Mass of Raw Materials in Enzymatic Reactions

preprint
submitted on 01.02.2021, 02:17 and posted on 02.02.2021, 07:35 by Masatoshi Kawashima
Correlation between the yield in the enzymatic reaction and the molecular weight of the substrate as an approximation of the reduced mass of the raw materials was clarified. The correlation was expressed by the same regression equation as in general organic chemical reactions. The coefficient of the regression equation to distinguish between intramolecular and intermolecular reactions were better when the values for intramolecular reactions were used in the plot of literature yields versus predicted yields. It was also found that the adjustment of the reduced mass by the number of rotatable bonds was not necessary and was found to be a good representation of the characteristics of the enzymatic reaction.

History

Email Address of Submitting Author

kawashima@azuma-g.co.jp

Institution

Azuma Co., Ltd.

Country

Japan

ORCID For Submitting Author

0000-0002-1849-2053

Declaration of Conflict of Interest

no conflict of interest

Version Notes

20210201-1

Exports

ChemRxiv

Exports