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Controlled Diffusion of Photoswitchable Receptors by Binding Antielectrostatic Phosphate Oligomers

preprint
submitted on 14.05.2020 and posted on 15.05.2020 by Thomas MacDonald, Ben L. Feringa, William S. Price, Sander J. Wezenberg, Jonathon Beves
Dihydrogen phosphate anions are found to spontaneously associate into anti-electrostatic oligomers via hydrogen bonding interactions at millimolar concentrations in DMSO. Diffusion NMR measurements supported formation of these oligomers, which can be bound by photoswitchable anion receptors to form large bridged assemblies of approximately three times the volume of the unbound receptor. Photoisomerization of the oligomer-bound receptor causes a decrease in diffusion coefficient of up to 16%, corresponding to a 70% increase in effective volume. This new approach to external control of diffusion opens prospects in controlling molecular transport.

Funding

Australian Research Council FT170100094 (J.E.B.)

Ministry of Education, Culture and Science (Gravitation Program 024.001.035) (S.J.W. and B.L.F.)

European Research Council Advanced Grant 694345 (B.L.F.)

European Research Council Starting Grant 694345 (S.J.W.)

History

Email Address of Submitting Author

j.beves@unsw.edu.au

Institution

UNSW Sydney

Country

Australia

ORCID For Submitting Author

0000-0002-5997-6580

Declaration of Conflict of Interest

No conflict of interest is declared.

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