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Chemical Reaction Monitoring Using Zero-Field Nuclear Magnetic Resonance Enables Study of Heterogeneous Samples in Metal Containers

preprint
submitted on 21.04.2020 and posted on 23.04.2020 by Dudari B. Burueva, James Eills, John W. Blanchard, Antoine Garcon, Román Picazo Frutos, Kirill V. Kovtunov, Igor Koptyug, Dmitry Budker

We demonstrate that heterogeneous/biphasic chemical reactions can be monitored with high spectroscopic resolution using zero-field nuclear magnetic resonance. This is possible because magnetic susceptibility broadening is insignificant at ultralow magnetic fields. We show the two-step hydrogenation of dimethyl acetylenedicarboxylate with para-enriched hydrogen gas in conventional glass NMR tubes, as well as in a titanium tube. The low frequency zero-field NMR signals ensure that there is no significant signal attenuation due to shielding by the electrically conductive sample container. This method paves the way for in situ monitoring of reactions in complex heterogeneous multiphase systems and in reactors made from conductive materials without magnetic susceptibility induced line broadening.

Funding

Marie Skłodowska-Curie Grant Agreement No. 766402

RFBR (19-29-10003)

Russian Ministry of Science and Higher Education (AAAA-A16-116121510087-5)

European Research Council Grant Agreement No. 695405

National Science Foundation CHE-1709944

History

Email Address of Submitting Author

eills@uni-mainz.de

Institution

Johannes Gutenberg Universität Mainz

Country

Germany

ORCID For Submitting Author

0000-0001-8468-6860

Declaration of Conflict of Interest

The authors declare no conflict of interest.

Licence

Exports